Sullivan Laboratory
The Sullivan Laboratory
Molecular, Cell, and Developmental Biology
University of California at Santa Cruz
Research Projects

Drosophila Early Development

The First Three Hours of Embryonic Development


Current Research Projects

Our research focuses on the structural and regulatory mechanisms that drive cell division.  Much of our effort has been directed toward understanding the mechanisms that drive furrow invagination during cytokinesis and how this process is regulated with respect to other mitotic events.  A second related focus of our group is to understand the mechanisms by which the widespread bacterial endosymbiont Wolbachia alters core host cellular processes to ensure its successful vertical transmission in insects.  This work has also led us to explore the origin of centrosomes in parthenogenetic insects.

Genetic Analysis of the Beginning of Life

Screens for mutations that specifically disrupt syncytial divisions.

Parthenogenesis

Cellular adaptations in the evolution of parthenogenesis.

Cytokinesis

The role of membrane addition in cleavage furrow formation

Checkpoints and Early Embryogenesis

Analyzing DNA damage and replication checkpoints in a developmental context.

  Wolbachia

  The molecular basis of   
  host-bacterial interactions


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Last updated: December, 2006